Immunomodulatory role of Interleukin-33 in large vessel vasculitis

Large vessel vasculitis.

The vasculitides affecting large and medium-sized vessels are heterogeneous. This group includes such disorders as giant cell arteritis, Takayasu's disease, and sarcoidosis. There are several challenges that may arise in the care of patients with these disorders. Diagnosis may be elusive when initially evaluating patients with large-vessel vasculitis. Most serologic markers are not specific, an...

Pericarditis Revealing Large Vessel Vasculitis

Large vessels vasculitis and more specifically, Giant cell arteritis, is characterized by increased inflammatory markers, headaches and altered clinical status. Diagnosis is confirmed by biopsy of temporal arteries showing the presence of granuloma and vasculitis. We hereby report the case of a patient presenting initially as pericarditis and revealing large vessel vasculitis using FDG-PET.

Medium- and large-vessel vasculitis.

N Engl J Med 2003;349:160-9. Copyright © 2003 Massachusetts Medical Society. nflammation of large arteries such as the aorta and its major branches occurs in a number of disorders, including Kawasaki’s syndrome, Behçet’s syndrome, rheumatoid arthritis, syphilis, and tuberculosis. However, aortitis and large-vessel arteritis are characteristics of two entities — giant-cell (temporal) arteritis a...

FDG-PET in Large Vessel Vasculitis

Large vessel vasculitis with myelodysplastic syndrome.

A 71-year-old woman presented with a high-grade fever, neck pain, anemia and thrombocytopenia. After performing further examinations, we concluded that she had simultaneously developed large vessel vasculitis and myelodysplastic syndrome (MDS). Although glucocorticoid administration improved her clinical symptoms, the MDS transformed into acute myeloid leukemia and she died one year after recei...